| abstract |
The present invention comprises a proton pump inhibitor, ie, an H + , K + -ATPase inhibitor, a gastric acid antisecretory prostaglandin analog and optionally an additional drug, such as a calcium channel blocker. It relates to a new oral dosage form, in particular for use in the treatment and prevention of gastrointestinal disorders. More particularly, the present invention relates to a novel dosage form consisting of omeprazole and misoprostol. The present invention also relates to combinations of three categories of drugs: H + , K + -ATPase inhibitors, gastric acid antisecretory prostaglandin analogs, and calcium channel blockers. Furthermore, the invention relates to a process for the preparation of the above-mentioned dosage forms and their use in medicine and to blister packs comprising these medicines. |