| abstract |
(57) [Summary]nThe present invention relates generally to valence molecules (eg, valence platform molecules, where one or more molecules act as a scaffold that can be covalently linked to form a conjugate). More particularly, the present invention relates to a valence platform molecule comprising a carbamate linkage (ie, -OC (= O) -N <). In one aspect, the invention relates to a valency platform comprising a carbamate linkage, wherein the molecule has a structure of any one of Formulas I, II, or III shown in FIG. In one aspect, the invention relates to a valency platform comprising a carbamate linkage, wherein the molecule has a structure of any one of Formulas IV, V, or VI shown in FIG. The present invention also relates to such valency platform molecules, conjugates comprising such valency platform molecules, and methods of preparing such conjugates. |