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filingDate 1999-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2002-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2002531450-A
titleOfInvention Process for producing paroxetine hydrochloride
abstract (57) [Summary]nBy crystallizing from a solution of paroxetine hydrochloride in propan-2-ol to which a crystal habit modifier compound has been added, crystalline paroxetine having a modified crystal habit that more easily desolvates to form an anhydride. A hydrochloride / propan-2-ol solvate is obtained. Heating a crystalline solvate having a modified crystal habit in a vacuum oven gives Form A anhydride. Suitable crystal habit modifiers are carboxylic acids and amine salts.
priorityDate 1998-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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