http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2002530390-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D253-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D253-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D253-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-14 |
| filingDate | 1999-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2002-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2002530390-A |
| titleOfInvention | IL-5 inhibitory 6-azauracil derivative |
| abstract | (57) [Summary]nIn the present invention, p is 0 to 3; q is 0 to 4; -AB- is-(CH Two ) r -,-(CH Two ) t -O-,-(CH Two ) t -S (= O) u -Or-(CH Two ) t -NR Three R is 2 to 4; t is 1 to 3; u is 0 to 2; 1 Is O, S, NR Three Or a direct bond; 1 And R Four Is C 1-6 Alkyl, halo, polyhalo C 1-6 Alkyl, hydroxy, mercapto, C 1-6 Alkyloxy, C 1-6 Alkylthio, C 1-6 Alkylcarbonyloxy, aryl, cyano, nitro, Het Three , R 6 , NR 7 R 8 Or substitution C 1-4 Alkyl; R Two Is aryl, Het 1 , C 3-7 Cycloalkyl, cyano, optionally substituted C 1-6 Alkyl, -C (= Q) -X Two -R Fifteen And R Three Is hydrogen or C 1-4 Alkyl; R Fifteen Is hydrogen, optionally substituted C 1-6 Alkyl, C 3-7 Cycloalkyl, aryl; X Two Is a direct bond, Fifteen But also halo or Het 1 Can also be; X Two Is NR Five R if Fifteen Can also be hydroxy; X Two Is C (= O) -NH-NH or NH-NH-C (= O), Fifteen Is R 11 Q can be replaced by O, S or NR Three And X Two Is O, S, NR Five , C (= O) -NH-NH, NH-NH-C (= O) or a direct bond; Five Is hydrogen, C 1-6 Alkyl, C 1-6 Alkyloxy or aryl C 1-6 Alkyl; R 6 Is a sulfonyl or sulfinyl derivative; R 7 And R 8 Is independently hydrogen, optionally substituted C 1-4 Alkyl, aryl, carbonyl-containing moiety, C 3-7 Cycloalkyl, -YC 1-4 Alkanediyl-C (= O) -OR 14 , Het Three And R 6 And R 11 Is hydroxy, mercapto, cyano, nitro, halo, trihalomethyl, C 1-4 Alkyloxy, formyl, trihalo C 1-4 Alkylsulfonyloxy, R 6 , NR 7 R 8 , C (= O) NR 7 R 8 , C 1-4 Alkanediyl-C (= O) -OR 14 , -C (= O) -OR 14 , -YC 1-4 Alkanediyl-C (= O) -OR 14 , Aryl, aryloxy, arylcarbonyl, C 3-7 Cycloalkyl, C 3-7 Cycloalkyloxy, phthalimido-2-yl, Het Three , Het Four And C (= O) Het Three An aryl is an optionally substituted phenyl; Het 1 , Het Two , Het Three And Het Four Is a heterocyclic ring which may be optionally substituted, their N-oxides, pharmaceutically acceptable addition salts and stereochemical isomers; Composition comprising the composition. The invention further relates to their use as medicaments.nEmbedded image |
| priorityDate | 1998-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 302.