abstract |
(57) Abstract. Benzopyrans, benzothiopyrans, dihydroquinolines, dihydronaphthalenes and analogs thereof have been described for use in the treatment of cyclooxynase-2 mediated diseases. Compounds of particular interest are defined by formula (I), wherein X, A 1 , A 2 , A 3 , A 4 , R, R ″, R 1 and R 2 are as described herein. There is |