http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2002525559-A
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6841 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6841 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-566 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-58 |
filingDate | 1999-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2002-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2002525559-A |
titleOfInvention | Method for detecting intrachromosomal imbalance in interphase nucleus, kit therefor and application thereof |
abstract | (57) [Summary] The present invention relates to (a) a chromosome suspected of being affected by intrachromosomal imbalance, which is labeled with a different fluorescent dye and has two specific arms for the long arm and the short arm of the chromosome. In situ hybridization using two probes; (b) measuring the fluorescence intensity emitted to the nucleus at different emission wavelengths corresponding to each of the two fluorescent dyes; (c) between the two measured fluorescence intensity values Detecting an intrachromosomal imbalance in the interphase nucleus, comprising: calculating the ratio (R a ) of the nuclei; and (d) comparing the value of the ratio obtained with at least one reference value. On how to do it. The invention also relates to a kit for performing the method, and in particular to detecting cancer cells in a biological sample and diagnosing cancer pathology, and the use of the method. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2013153704-A |
priorityDate | 1998-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 59.