http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2002525290-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N1-0247 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N1-0273 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61J3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N1-02 |
| filingDate | 1999-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2002-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2002525290-A |
| titleOfInvention | Apparatus and method for maintaining and / or restoring organ viability |
| abstract | (57) [Summary]nMonitoring and maintaining and / or restoring the viability of the organ prior to perfusing the organ at low temperatures (low temperature perfusion mode) to transport and / or store the organ; At normal temperature, the organ is perfused (normal temperature perfusion mode) to preserve the organ for transport and / or transfer, and then the organ is perfused at low temperature for transport and / or storage (low temperature). Temperature perfusion mode). By perfusing the organ at normal temperature with a medical fluid, such as a bicarbonate medical fluid based on oxygenated cross-linked hemoglobin, high-energy nucleotides in the organ reduced due to warm ischemia time ( Restoring organ viability is achieved by restoring ATP) levels, for example. In the normal temperature perfusion mode, the organ perfusion pressure is preferably controlled by a pneumatically pressurized medical fluid reservoir in response to a sensor located at the end of a tube located within the organ. The medical fluid reservoir is used in combination with a step motor operated cam valve that finely regulates the perfusion pressure, prevents over-pressurization, and shuts off flow in an emergency. In the low temperature perfusion mode, the organ is perfused intermittently or with a slow, continuous flow with a medical fluid, preferably a monocrystalline solution enriched with an antioxidant. Medical fluid is supplied to the organ by gravity from an intermediate tank with a low pressure head so that the organ is not overpressurized. In either perfusion mode, over-pressurization is prevented, preventing damage to the vascular endothelial lining, and generally to organ tissue. Also, preferably, in any mode, the viability of the organ is automatically monitored by monitoring the fluid properties of the medical fluid perfused into the organ, such as a fluid property indicative of the viability of the organ. I do. A control program can be used to automatically control the perfusion process. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021005988-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2007519763-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2013536804-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008515914-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2021152035-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2015527997-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7110449-B2 |
| priorityDate | 1998-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 323.