| abstract |
(57) [Summary]nThe present invention relates to a Moraxella catarrhalis outer membrane protein polypeptide and a polypeptide derived therefrom (collectively referred to as “OMP21”), a nucleotide sequence encoding OMP21, and an antibody that specifically binds to OMP21. Disclose. Also disclosed are pharmaceutical compositions containing OMP21, antibodies to OMP21, or nucleotides encoding OMP21, which may be a prophylactic or therapeutic composition, or an immunogenic composition such as a vaccine. The invention further discloses a method of eliciting an immune response to Moraxella catarrhalis and OMP21 in an animal (preferably a human), a method of treating and diagnosing Moraxella infection in an animal (preferably a human), and a kit therefor. |