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filingDate 1999-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2002-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2002525066-A
titleOfInvention Transcriptional methods for specific cellular localization of nucleic acids
abstract (57) [Summary]nThe present invention relates to a novel method of genetic mutation. There, the nucleic acid of interest is moved across the biomembrane and / or in a specific direction to a specific location or cell, using a synthetic transport entity. The transport entity according to the invention is novel and thus a binding element (BE), such as a peptide nucleic acid, a functional element (FE) for PNA (for example, a nuclear translocation signal of a protein consisting of membrane translocation and nuclear transport properties). (NLS), the antennal pedia peptide), are generated by the linker molecule, preferably by dissociated conjugation. And it hybridizes to the BE target sequence that is then present on the carrier. And it also includes interest nucleic acids. The current nucleic acid of interest may be, for example, a gene encoding a peptide (protein or ribosomal ribonucleic acid) or any other nucleic acid useful for a gene recombination event.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008527993-A
priorityDate 1998-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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