abstract |
(57) Abstract: The present invention has one or more non-hereditary bulky and lipophilic amino acids and one or more cationic residues having esters, amides, salts and cyclic derivatives thereof. Provided are 7 to 25-mer cytotoxic peptides, methods for producing such peptides, pharmaceutical compositions containing them, and their use as medicaments, particularly as antimicrobial or antitumor agents. |