| abstract |
Abstract: A method and apparatus for forming an in situ tissue adhesive barrier using a sprayer (90) that can apply two or more viscous crosslinking solutions to tissue is provided. The sprayer (90) comprises a separate sprayer nozzle (98, 100) for each of the two or more crosslinking solutions, wherein each nozzle (98, 100) is connected to a gas pressurized chamber (48), and It may also include a valve (52) to prevent backflow through the supply line (99, 100) carrying the crosslinking solution, and a venting system (106, 108) to vent excess pressure for laparoscopic applications. . In the presence of a gas stream, the crosslinking solution is sprayed and mixed to form a spray. Multicomponent hydrogel systems and devices suitable for use in the method of the invention are also described. |