| abstract |
(57) [Summary]nDisclosed are compositions and methods using the optically pure (+) isomer of norcis apide. Surprisingly, it has been found that this compound is a potent drug for treating disorders of the central nervous system. This compound (+) norcis aplide was also found to be a potent antiemetic. Finally, the (+) isomer of norcis apride also avoids certain deleterious side effects and certain deleterious drug interactions. In addition, the compounds are useful in treating gastrointestinal motility dysfunction, gastroesophageal reflux disease, dyspepsia, gastroparesis, and pseudo-ileus. This has a prokinetic effect. |