| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-101
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-1016
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-1019 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-103
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-107
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08 |
| filingDate |
1999-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2002-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2002520331-A |
| titleOfInvention |
Method for coupling amino acids using bis-trichloromethyl carbonate |
| abstract |
(57) [Summary]nDisclosed are methods for using triphosgene as an efficient and effective coupling agent in peptide synthesis by in situ production of amino acid chlorides from protected amino acids. This method is particularly useful for coupling to sterically hindered amino acid residues or for coupling with other difficulties. In addition, the same reagents can be used for derivatization of the peptide by forming an amide bond between the free amine and the carboxylic acid on the peptide, or for coupling the amino acid to a solid support. |
| priorityDate |
1998-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |