http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2002519356-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-1077 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-61 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-107 |
| filingDate | 1999-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2002-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2002519356-A |
| titleOfInvention | Improved process for the preparation of Schiff base adducts of o-hydroxyaldehydes and amines, and composition of substances based thereon |
| abstract | (57) [Summary]nAn improved method for producing a Schiff base condensation addition end product comprising as an ingredient a protein having beneficial activity in animals and an aromatic o-hydroxyaldehyde is described. The method comprises combining the aforementioned components in an aqueous environment having a pH of 7.0 or more to form a reaction mixture, wherein the condensation reaction is carried out with about 97.0% of the water existing or produced during the condensation reaction. Effective to substantially complete by removing from about 99.9% to about 99.9%, preferably from about 98.0% to about 99.0%, maintaining the integrity of the condensation reactant and the added end product. And that the conversion to said condensation addition end product, i.e. the resulting yield of said condensation addition end product, is at least about 98.5% by weight, preferably about 98.5% by weight, based on the weight of the reactants. The reaction is carried out under conditions such that the amount is 99.5% by weight or more. Preferred aromatic o-hydroxyaldehydes are o-vanillin; salicylaldehyde; 2,3-dihydroxybenzaldehyde; 2,6-dihydroxybenzaldehyde; 2-hydroxy-3-ethoxybenzaldehyde; or pyridoxal. A very wide range of proteins can be used. The improved method provides a yield of over 90% and substantially quantitative conversion of aldehydes and proteins to condensed adducts. |
| priorityDate | 1998-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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