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filingDate 1999-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2002-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2002518430-A
titleOfInvention Transdermal therapeutic system including hormone and crystallization inhibitor
abstract (57) [Summary]nThe present invention is a patch form transdermal therapeutic system for controlled release of estradiol in combination with norethisterone acetate, comprising a backing layer, attached thereto, prepared using a polyacrylate pressure sensitive adhesive and a crystallization inhibitor. Transdermal therapeutic system comprising a reservoir supersaturated with an active ingredient as well as a removable protective layer. The system of the invention is characterized in that the crystallization inhibitor is a polymer containing amino groups.
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