| abstract |
(57) [Summary]nThe present invention provides methods and compositions for the treatment of refractory depressive states relative to the typical anti-depressive treatment alone. In these methods and compositions, atypical antipsychotics and compounds having activity as serotonin reuptake inhibitors are used. The present invention also provides a method of providing rapid-acting treatment of severe depression, wherein the method uses an atypical antipsychotic and a compound having activity as a serotonin reuptake inhibitor. |