http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2002516086-A
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-91 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-22 |
filingDate | 1998-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2002-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2002516086-A |
titleOfInvention | Novel endonuclease of immune cells, method for producing the same and immunoadjuvant using the same |
abstract | (57) [Summary]n The present invention relates to a novel endothelium that is secreted from immune cells and recognizes bacterial DNA as a foreign substance and processes it to produce a single-stranded oligonucleotide of about 10 base pairs containing a CpG motif involved in the immune response. For nucleases. The present invention also provides a method for producing the endonuclease, comprising culturing the human B-lymphoblastic IM9 cell line or the myeloid U937 cell line treated with TPA in a suitable medium. , And isolating the endonuclease from a cell lysate or culture medium. In addition, the present invention relates to an immunoadjuvant comprising an approximately 10 base pair single-stranded oligonucleotide having a CpG motif, produced by treating bacterial DNA with its endonuclease. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009060909-A |
priorityDate | 1998-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 443.