abstract |
(57) The present invention provides a compound represented by the general formula (I): (Wherein X, Y, Z, R 1 , R 2 and r are as defined herein), or a salt thereof, to a process for preparing them. , In compositions comprising them, and for the clinical treatment of painful, hyperalgesic and / or inflammatory conditions in which C-fibers play a pathophysiological role by inducing neurogenic pain or inflammation And the use for the treatment of conditions caused or related to the secretion and circulation of insulin antagonistic peptides, such as non-insulin dependent diabetes mellitus (NIDDM) and aging-related obesity. |