| abstract |
(57) [Summary]nAttenuated recombinant viruses having DNA encoding canine distemper virus antigen or measles M or N antigen are disclosed and claimed, along with methods and compositions using the virus. The recombinant virus may be a NYVAC or ALVAC recombinant virus. The DNA may encode at least one of a canine distemper virus fusion protein, a canine distemper virus hemagglutinin glycoprotein, a canine distemper nucleocapsid protein, a canine distemper matrix protein, a measles virus nucleocapsid glycoprotein, and a measles virus matrix protein. . The recombinant viruses and gene products therefrom, and the antibodies induced by them, are useful for inducing protection against canine distemper virus and / or measles virus, and the gene products and the antibodies induced by them are assayed. It is useful in In addition, DNA from recombinants is useful for generating PCR primers or as a probe. |