http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2002514631-A
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-24 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-426 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4245 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-421 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-422 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-04 |
filingDate | 1999-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2002-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2002514631-A |
titleOfInvention | Oxazole-aryl-carboxylic acids useful for treating insulin resistance and hyperglycemia |
abstract | The present invention is useful for treating metabolic disorders associated with insulin intolerance or hyperglycemia, wherein R is (a) or (b); A is OR 5 or (c). R 1 is alkyl containing 1-6 carbon atoms, cycloalkyl containing 3-8 carbon atoms, thienyl, furyl, pyridyl, (d) or (e); R 2 is Hydrogen, alkyl containing 1-6 carbon atoms or aryl containing 6-10 carbon atoms; R 3 and R 4 are independently halogen, hydrogen, containing 1-12 carbon atoms Alkyl, aryl containing 6-10 carbon atoms; halogen, trifluoromethyl containing 1-6 carbon atoms, alkoxyaryl containing 7-14 carbon atoms; nitro, amino, carboalkoxy, carbamide, carbamate , Urea Alkylsulfonyl amides, -NR 7 (CH 2) m CO 2 H, aryl sulfonamide, cycloalkyl containing 3-8 carbon atoms, or oxygen, 1 to 3 hetero atoms selected from nitrogen or sulfur R 5 is hydrogen, alkyl containing 1 to 6 carbon atoms, —CH (R 8 ) R 9 , —C (CH 2 ) n CO 2 2 R 10, -C (CH 3 ) 2 CO 2 R 10, -CH (R 8) (CH 2) n CO 2 R 10, -CH (R 8) C 6 H 4 CO 2 R 10 or -CH 2 - be a tetrazole; R 6 is hydrogen, alkyl containing 1-6 carbon atoms, halogen, alkyloxy containing 1-6 carbon atoms, trifluoroalkyl or 1 containing 1-6 carbon atoms A structure that is a trifluoroalkoxy containing 6 carbon atoms ( ) [Formula 1] Or a pharmaceutically acceptable salt thereof of formula (I) having the formula: |
priorityDate | 1998-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 274.