http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2002514442-A
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-22 |
filingDate | 1999-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2002-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2002514442-A |
titleOfInvention | Heteroduplex mutant vectors and their use in bacteria |
abstract | (57) [Summary]nThe present invention is based on the discovery that recombinant progenitor oligonucleobases are active in prokaryotes with strand transfer activity (RecA) and mismatch repair activity (MutS). Using this system, in prokaryotic cells, a type of double-stranded mutant vector called a heteroduplex mutant vector was found to be more active than the types of mutant vectors tested so far. . By replacing the tetrathymidine linker with a nuclease-resistant oligonucleotide such as tetra-2'-O-methyl-uridine, joining the two strands of the recombinogenic oligonucleobase and removing the DNA-containing intervening segment, Has been further improved. The claims relate to double-stranded mutant vectors containing the above-mentioned improvements. In another embodiment, the claims relate to the use of the double-stranded mutant vector in prokaryotic cells. |
priorityDate | 1998-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 312.