| abstract |
SUMMARY OF THE INVENTION The present invention provides vitamin PP compounds and / or compounds for the reduction, elimination or prevention of different degrees of side effects and neutralization of acute side effects, particularly in immunosuppression or anticancer chemotherapy or diagnosis with substituted pyridinecarboxamides. Or the use of compounds having anti-pellagra activity, such as nicotinic acid (niacin), and nicotinamide (niacinamide, vitamin PP, vitamin B3). Thereby a series of compounds from formula (I) And combinations of certain amounts of this compound with vitamin B3 and / or anti-pellagra activity and chemotherapeutic agents are particularly contemplated for the above chemotherapies and indications. |