abstract |
(57) Summary The present invention relates to a method for producing a compound of formula (b) by reacting a compound of formula (V) with a compound of formula (VI). The resulting compound of formula (IV) is reduced to a compound of formula (III), which is hydrolyzed to a compound of formula (b). Alternatively, the compound of formula (IV) is hydrolyzed to a compound of formula (a), which is reduced to a compound of formula (b). The compounds of the formula (IV) are new. The variables in the formula are as defined in the claims. Compounds of formula (b) are useful as intermediates in the manufacture of matrix metalloproteinase inhibitors. Embedded image |