http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2002511390-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D251-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D251-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D251-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D251-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D251-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D251-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D251-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D251-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D251-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D251-70 |
| filingDate | 1999-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2002-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2002511390-A |
| titleOfInvention | Trisubstituted 1,3,5-triazine derivatives for the treatment of HIV infection |
| abstract | SUMMARY OF THE INVENTION The present invention provides a compound of formula (I) for the manufacture of a medicament for treating a patient suffering from HIV (human immunodeficiency virus) infection. Wherein A is CH, CR 4 or N; n is 0, 1, 2, 3 or 4; R 1 and R 2 are each independently hydrogen, hydroxy, C 1-12 alkyl, C 1 -12 alkyloxy, C 1-12 alkylcarbonyl, C 1-12 alkyloxycarbonyl, aryl, amino, mono- - or di (C 1-12 alkyl) amino, mono- - or di (C 1-12 alkyl) aminocarbonyl Wherein each of the above C 1-12 alkyl groups is optionally and each independently substituted; or R 1 and R 2 taken together are pyrrolidinyl, piperidinyl, morpholinyl, azide or Mono- or di (C 1-12 alkyl) amino C 1-4 alkylidene may be formed; R 3 is hydrogen, aryl, C 1-6 alkylcarbonyl, optionally substituted C 1-6. With alkyl And each R 4 is independently hydroxy, halo, C 1-6 alkyl, C 1-6 alkyloxy, cyano, aminocarbonyl, nitro, amino, trihalomethyl or trihalomethyloxy; L is —X— R 5 or a -X-Alk-R 6, wherein, R 5 and R 6 are each independently indanyl, be indolyl or phenyl; said indanyl, each of indolyl or phenyl may be optionally substituted; and X is -NR 3 -, - NH-NH -, - N = N -, - O -, - S -, - S (= O) - or -S (= O) 2 - a and; aryl If Het is an optionally substituted aliphatic or aromatic heterocyclic residue; N-oxides thereof, pharmaceutically acceptable Addition salt and standing On the use of chemical isomers. It further relates to novel compounds which are a subgroup of the compounds of formula (I), their preparation and pharmaceutical compositions comprising them. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-4783725-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008509200-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2006516983-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2005526846-A |
| priorityDate | 1998-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 231.