abstract |
(57) [Summary]nDisclosed are novel polynucleotides and the secreted proteins encoded thereby. The protein can be used, for example, as a therapeutic to stimulate blood cell production in patients undergoing cancer chemotherapy, to treat bone marrow transplant patients, and to heal broken bones. A polynucleotide of the invention can be used therapeutically to provide a protein of the invention. The polynucleotides of the present invention can also be used diagnostically, for example, on a polynucleotide array, to detect differential gene expression in diseased tissue compared to gene expression in normal tissue. |