abstract |
(57) [Summary]nThe present invention is directed to agonists of neuropeptide Y (NPY) or PYY, wherein the agonists are formed by binding of these peptides, or a portion of these peptides, to a template that promotes a biologically active fold. Have been. Typically, the template consists of a cyclic peptide containing one or more naphthyl ring structures. Agonists can be used for the treatment of diseases and conditions known to respond to NPY or PYY, especially for the treatment of asthma, rhinitis and bronchitis. |