Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0331 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-072 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2207-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-30 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0278 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0275 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4746 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8509 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 |
filingDate |
1999-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2002-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-2002508960-A |
titleOfInvention |
Transgenic non-human mammal, method for producing the same and use thereof |
abstract |
(57) [Summary] The present invention provides a method for transfecting a non-human mammal embryonic stem cell line with an appropriate recombinant vector, isolating a stably transfected cell clone, and appropriately transfecting the non-human mammal. All or part of the p53 gene during the recombination event is transplanted into a prepared female animal and selected for progeny based on the presence of the gene exchange. The present invention relates to a method for producing a transgenic non-human mammal, characterized in that each sequence functionally replaced by a p53 gene segment and introduced can be used as a genomic sequence. The present invention also relates to the resulting transgenic non-human mammals and their use for drugs, chemicals and therapeutic approaches or therapeutic uses. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017026383-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2017026383-A1 |
priorityDate |
1998-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |