http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2002508313-A
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-166 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-166 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C257-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-606 |
filingDate | 1998-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2002-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2002508313-A |
titleOfInvention | Substituted amidino compounds in the treatment of chronic obstructive pulmonary disease |
abstract | (57) Abstract: In a medicament for the treatment of chronic obstructive pulmonary disease, the formula: Wherein the C (= NH) —NHR 3 group can be an isomer or an isomer: R 1 is selected from aliphatic, allaliphatic, aromatic and cycloaliphatic hydrocarbon groups. R 2 is hydrogen, halogen, trifluoromethyl, or an amino mono- or di-substituted by a substituent or an amino di-substituted by a divalent aliphatic hydrocarbon group or an oxygen-interrupted group. An aliphatic hydrocarbon group, hydroxy, or hydroxy, etherified with an aliphatic, araliphatic or aromatic alcohol, or an aliphatic alcohol substituted with carboxy, esterified carboxy or amidated carboxy, or aliphatic or R 3 is hydrogen esterified with an araliphatic carboxylic acid; R 3 is hydrogen or an organic carbonic acid, an organic carboxylic acid, sulfuric acid. X 1 and X 3 independently of one another are oxygen (—O—) or sulfur (—S—); and X 2 is an acyl group derived from an acid or carbamic acid; Good divalent aliphatic hydrocarbon radicals; the phenyl rings of the formula I independently of one another are halogen, trifluoromethyl, aliphatic hydrocarbon radicals, hydroxy and aliphatic etherified by hydroxy and aliphatic alcohols, or aliphatic. Or further substituted with one or more substituents selected from hydroxy esterified by araliphatic carboxylic acids; aryl as defined above, independently of one another, further halogen, trifluoromethyl, aliphatic Hydroxy or aliphatic or araliphatic carboxy etherified with hydrocarbon groups, hydroxy, and aliphatic alcohols Or a cycloaliphatic hydrocarbon group can be further substituted with an aliphatic group] or a pharmaceutically acceptable salt thereof. Use of acceptable salts. |
priorityDate | 1997-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 68.