| abstract |
(57) [Summary]nThe present invention relates to the use of specific gene combinations in gene therapy. By simultaneously delivering multiple genes to target cells, the effect of one or both genes is increased. This is particularly effective in attacking diseased cells, such as those that make hyperplastic or neoplastic tissue. Classes of genes that can be used in combination are tumor suppressors, cytokines and lymphokines, toxins, inducers of apoptosis, antisense oncogenes, single-chain antibodies, ribozymes, transcription factors and regulators, cell cycle regulators and enzymes. |