| abstract |
(57) The present invention provides a compound represented by the general formula (I): wherein R 1 represents hydrogen or an alkyl or cycloalkylmethyl group, X 1 represents hydrogen or a halogen or an alkoxy group, or OR 1 and X 1 has the formula -OCH 2 O together -, - O (CH 2) 2 -, - O (CH 2) 3 -, - O (CH 2) 2 O- or -O (CH 2) 3 O- at X 2 represents a hydrogen atom, an amino group or a group represented by the general formula —NHCO 2 R—, wherein R represents an alkyl or phenylalkyl group; and X 3 represents hydrogen or R 2 represents hydrogen or a compound represented by an alkyl, phenylalkyl or [(4-dimethylamino) piperidin-1-ylcarbonyl] alkyl group. The invention is applicable to therapy. The compounds can be used in the treatment or prevention of disorders involving the 5-HT4 receptor in the central nervous system, gastrointestinal system, cardiovascular system or urinary system. |