http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2002503497-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5152 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-70503 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2833 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0011 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-574 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 |
| filingDate | 1999-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2002-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2002503497-A |
| titleOfInvention | Method for selecting a tumor susceptible to anticancer therapy expressing HLA-G and use thereof |
| abstract | (57) [Summary]n The present invention relates to a method of selecting a solid tumor that expresses HLA-G and is susceptible to anti-cancer therapy, which therapy suppresses or prevents HLA-G activity of the tumor, and uses thereof. The method can establish either the HLA-G transcription profile of a solid tumor or the HLA-G expression profile of a solid tumor. Methods for establishing HLA-G transcription profiles include (i) removal of tumor samples; (ii) extraction of mRNA; (iii) reverse transcription (RT) of the RNA; (iv) specific for each HLA-G isoform. Continuous or simultaneous amplification of the cDNA obtained in (iii) in the presence of various primers and analysis of the amplification products obtained by electrophoresis and / or specific hybridization, and (v) HLA of the sample -G Establishing a transcription profile. Methods for establishing the HLA-G expression profile include (i) removal of a tumor sample; (ii) labeling of cells in the sample, if necessary; (iii) performing cell lysis; Contacting the isolated cells with various antibodies against class I HLA-G antigens to form HLA-G isoform / antibody complexes as needed, and (v) determining the HLA-G expression profile of the sample. Establishing by detecting the complex formed in step (iv). |
| priorityDate | 1998-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 162.