| abstract |
(57) [Summary]nThe present invention relates to a novel anti-angiogenic protein for thrombospondin. More particularly, provided are isolated nucleic acid molecules encoding human METH1 and METH2. METH1 and METH2 polypeptides are also provided as are vectors, host cells, and recombinant methods for producing this material. Also provided are diagnostic methods for predicting cancer, as well as therapeutic methods for treatment of an individual in need of an increased amount of METH1 or METH2. |