abstract |
(57) [Summary]nThe present invention relates to caries preventive delivery vehicles, especially chewing gums, candies, confectioneries, toothpastes, dentifrices and gels. In particular, the present invention relates to chewing gums, candies, confectioneries containing a non-toxic slightly soluble calcium compound and a phosphate compound as additives, and gradually and constantly releasing calcium ions and phosphate ions into the oral cavity over a period of 5 minutes or more. Provide toothpaste, dentifrice and gel. The present invention releases calcium phosphate ions that diffuse into partially demineralized tooth enamel or dentin, resulting in mineral recruitment and repair of carious lesions, plaque, open dentinal tubules and exposed dentin Things. Accordingly, the present invention provides agents and methods for reducing or eliminating caries attack in plaques after dental mineral supplementation and sucrose ingestion. Thus, the formulations of the present invention can produce an effective caries prevention without the use of fluoride. In addition, hypersensitive teeth can be desensitized using the formulations of the present invention. |