http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2002500075-A
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-14532 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M2037-0007 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M37-0092 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M37-00 |
filingDate | 1999-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2002-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2002500075-A |
titleOfInvention | Transdermal transport enhanced by ultrasound transmission |
abstract | (57) [Summary]nA method of enhanced transdermal delivery, wherein for transdermal extraction or transdermal delivery repeated or sustained over a period of time, the application of ultrasound is performed rather than prior to each extraction or delivery. A method that is needed only once. The method is applicable to analyte extraction as well as drug delivery. The method involves the initial application of an effective amount of low frequency ultrasound to make the skin or membrane permeable, followed by extraction of the analyte or delivery of the drug over a period of time. This initial application of ultrasound is effective to render the skin or membrane permeable for at least about 30 minutes, preferably for at least 1-2 hours, and more preferably for up to 4-10 hours. The ultrasound is preferably a low frequency ultrasound of less than 2.5 MHz, more preferably less than 1 MHz. Transdermal transport can be enhanced by the application of a second driving force, such as suction, osmotic gradients, concentration gradients, iontophoresis, electroporation, magnetic fields, additional ultrasound, or mechanical pressure. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-4599872-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2005287776-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2013135851-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008541975-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2006512573-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007060741-A1 |
priorityDate | 1998-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 179.