| abstract |
PROBLEM TO BE SOLVED: To provide a medicament which has dipeptidyl peptidase IV inhibitory properties and is useful for treating diseases associated with glucose intolerance and hyperglycemia. SOLUTION: Formula (I): (Wherein ring A is a 5-membered nitrogen-containing heterocycle optionally substituted with a cyano group; Ak is straight-chain or branched-chain (C 1 -C 6) alkylene chain; X represents a single bond, etc.; R 1 and R 2 Is a hydrogen atom or the like; R 3 is a linear or branched (C 1 -C 6 ) alkyl or the like; Y is CH—NO 2 Etc.), its mutual isomers, their optical isomers and their addition salts with pharmaceutically acceptable acids, their synthesis, and pharmaceutical compositions containing them. |