http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2002363080-A

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filingDate 2001-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_587d58ec504a4e8e625dea31452865cc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_448e360d41f0002a0bfdd2aa55cc7940
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publicationDate 2002-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2002363080-A
titleOfInvention Manufacturing method of stable anti-ulcer preparation for internal use
abstract PROBLEM TO BE SOLVED: To provide excellent storage stability mainly using antiulcer drugs (omeprazole, lansoprazole and rabeprazole) having a basic skeleton in which 2-pyridylmethylsulfinyl group is substituted at the 2-position of benzimidazole. Provided is a method for producing an enteric coated tablet. SOLUTION: Granules containing a mixture of an anti-ulcer drug and an alkali compound selected from the group consisting of omeprazole, lansoprazole and rabeprazole or granules containing an alkali salt of the drug are granulated, and the granules are formed with a film-forming water-soluble polymer. A method for producing a stable oral anti-ulcer formulation, comprising coating, coating the coated granules, and coating the resulting naked tablet with an enteric polymer.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105232334-A
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