| abstract |
(57) [Summary] [Problem] To provide a skin external preparation which suppresses complex skin inflammatory reactions and the like and synergistically improves the effects of preventing and improving skin roughness, skin damage and aging. SOLUTION: One or two or more or 4 ', 7-dihydroxyisoflavones selected from an extract and an extract fraction of cuckoo ( Puerariae Radix ) and a cell activator are used in combination with a skin external preparation base. To be included. As the cell activator, yeast extract and yeast culture supernatant, asparagus, avocado, extracts of plants having a specific cell activator such as Aloe plants, hydroxy fatty acids and salts and derivatives thereof, nucleic acids and related substances, It is preferable to use one or more selected from a mixture of a protein and an isomerized saccharide extracted from an eggshell membrane. |