| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c76ecadad74a1a35270b3e3a34d60f37 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-4736 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-485
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-573
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5011
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-502
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-573
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
| filingDate |
2001-05-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e949f5c7c4f938d3b1088afd4fad6b5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a25b49f4197180a2b20496cd05e9c3d5 |
| publicationDate |
2002-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2002350438-A |
| titleOfInvention |
Assay method for cyclin-dependent kinase |
| abstract |
PROBLEM TO BE SOLVED: To provide a novel method for measuring the activity of one or more cyclin-dependent kinases (CDKs) in a sample based on quantification of a CDK-phosphorylated Rb protein. SOLUTION: The present cyclin-dependent kinase (CDK) The method of measuring the activity is as follows: i) contacting the sample with an anti-retinoblastoma protein (Rb) capture antibody that specifically recognizes CDK phosphorylated Rb; ii) contacting the capture antibody-Rb complex Contacting with an anti-Rb primary antibody, and isolating the capture antibody-Rb-primary antibody complex; and iii) quantifying the primary antibody present in the capture antibody-Rb-primary antibody complex. As a result, C in the above sample Measuring the amount of DK-phosphorylated Rb. The method involves the use of intracellular C in cultured cells or cells taken from animals. Can be used to assess DK activity. Also disclosed are methods for identifying agents that modulate the activity of a CDK. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7888050-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8114617-B2 |
| priorityDate |
2000-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |