| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7f6e33603375c486b0ab3505830af9e8 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-505
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-10 |
| filingDate |
2001-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e7045d6f996033db8300e8b2c20118eb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed8ac5807d3c53bc2cb88101736ec888
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3dba0a23f059398260237e061d4320da
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_60b6c81349dac15cd478906c8198dbf2 |
| publicationDate |
2002-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2002338599-A |
| titleOfInvention |
Physiologically active protein with improved blood retention and method for preparing the same |
| abstract |
[PROBLEMS] To provide a modified bioactive protein having a long residence time in blood. A modified bioactive protein to which dextran sulfate is bound by reacting the bioactive protein with dextran sulfate under alkaline conditions. It is desirable to use dextran sulfate sodium sulfur 5 as dextran sulfate. As bioactive proteins, cytokines such as erythropoietin and tumor cell-damaging factor are used. [Effect] The residence time of the physiologically active protein in blood can be extended. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8329186-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10196625-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015046602-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009536952-A |
| priorityDate |
2000-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |