http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2002330766-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1010e3862914acdd087e73d76911ec6d |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
| filingDate | 2001-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f55c3e87f3d9771ad787d79f65e08ba1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0672b82bed7071c6933576a88fd0bc46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b3f73886b8949f354a2498865f376bf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dad9a309ab354ebb7ce21b94e67fea07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f974e2e312a3dce78edb7e63a47a6a5b |
| publicationDate | 2002-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2002330766-A |
| titleOfInvention | Variant of protein that binds to Mec1 of budding yeast, and DNA for producing the variant |
| abstract | (57) [Summary] [PROBLEMS] To search for a protein that binds to Mec1 of budding yeast belonging to an ATM-related factor, to provide a mutant of the protein, and a DNA for producing the mutant. SOLUTION: A factor Pie1 interacting with Mec1 in budding yeast was isolated, and the function of Pie1 in checkpoint control was analyzed, and mutants pie1-KA and pie1-ΔC of the protein were produced. pie1-K A is a mutant in which the lysines at positions 177 and 178 of Pie1 have been substituted with alanine. A mutant in which amino acids have been deleted. Experiments have shown that these mutants result in abnormalities in the control of cell proliferation and checkpoint response. |
| priorityDate | 2001-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 426.