| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7ef01e33058cf740cf2197991be97af1 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-173 |
| filingDate |
2001-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7cd4b2248cf74aad8ae700b745fb9116
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ddc141cc0c13af094ab746139d3ac0f8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e91a5251f50b05cc3518fb15961cdc37 |
| publicationDate |
2002-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2002302498-A |
| titleOfInvention |
Industrial production of nucleosides |
| abstract |
(57) [Problem] To provide a method for producing a nucleoside without isolating a 1-phosphorylated saccharide derivative as a crystal. SOLUTION: General formula (1) Or a salt thereof, after removing the hydroxymethyl group of R 1 and R 2 , the protecting group of the carboxyl group, or the protecting group of the hydroxyl group of R 4 , by an exchange reaction between a phosphate group and a nucleobase. In a method for synthesizing a nucleoside, the elimination reaction and the exchange reaction between a phosphate group and a base are carried out in a water-soluble solvent to obtain a compound of the general formula (3) Or a salt thereof without isolation as a crystal. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10464965-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9073960-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9441007-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-RE48171-E
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10485815-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11021509-B2 |
| priorityDate |
2001-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |