abstract |
(57) [Summary] (Modifications) [Problem] To provide a novel protease (USP) having deubiquitinating activity and a peptide or polypeptide derived therefrom, a polynucleotide encoding these, and To provide a method for producing a novel USP-derived peptide or polypeptide. The polypeptide has a specific amino acid sequence derived from human, a polypeptide containing the polypeptide, has at least about 70% amino acid sequence homology with the polypeptide, and has deubiquitination activity. A polypeptide selected from the group consisting of a polypeptide, a polypeptide having a mutation such as deletion, substitution, addition or insertion of one or several amino acids in the amino acid sequence, and a deubiquitinating activity, and the polypeptide Or a complementary strand thereof. |