abstract |
(57) [Problem] To provide a compound capable of suppressing the production of inflammatory cytokine. SOLUTION: The compound having the following general formula (I), or a pharmacologically acceptable salt, ester or other derivative thereof: {A: pyrrole; R 1 : substituted aryl, substituted heteroaryl; R 2 : substituted heteroaryl; R 3 : bicyclic amino group; R 4 , R 5 : H, substituted cycloalkyl, Substitutable aryl, substitutable heteroaryl, substitutable heterocyclyl. However, the atoms on the pyrrole ring to which R 1 and R 3 are bonded are respectively adjacent to the atoms on the pyrrole ring to which R 2 is bonded. } |