| abstract |
(57) [Summary] (Modified) [PROBLEMS] To provide Frizzled-3 polypeptides and polynucleotides. A Friz comprising an amino acid sequence having at least 99% identity to a particular amino acid sequence A Frizzled-3 polynucleotide comprising a zled-3 polypeptide and a nucleotide sequence having at least 95% identity to a particular nucleotide sequence is obtained. Frizzled-3 polypeptides and polynucleotides are useful in treating dysfunctions or diseases, including nervous system diseases such as schizophrenia, and in diagnostic assays for such diseases. |