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filingDate 2001-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c1dd4cfaab0523334279a2b5f896a47
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publicationDate 2002-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2002250730-A
titleOfInvention Molecular sensor and manufacturing method thereof
abstract (57) [Problem] To provide a molecular sensor for a second messenger in a living body and a method for producing the same. SOLUTION: A molecular sensor in which the vicinity of a substrate binding site of a PH domain is labeled with a fluorescent molecule; an amino acid residue around the substrate binding site is mutated to cysteine, and the fluorescent molecule is selectively reacted with the mutated cysteine residue. A method for producing a molecular sensor.
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