| abstract |
(57) [Problem] To be used alone or in a high blending ratio, have high hardness, high content of the main drug, excellent phosphate binding ability, and reduce the effect of stirring strength in the acidic to neutral range. A phosphate-binding polymer capable of forming a tablet that exhibits rapid disintegration that is difficult to undergo, and can provide an excellent preparation that can reduce fluctuations in bioavailability due to movement in the digestive tract and pH when tableted. The development of acid-binding polymers has been desired. SOLUTION: The formula: A phosphate-binding polymer having a true specific gravity of 1.18 to 1.24; a tablet containing the polymer alone or, if necessary, microcrystalline cellulose and / or low-substituted hydroxypropylcellulose; and a tablet thereof. Manufacturing method. |