| abstract |
(57) [Problem] To provide a compound which directly or indirectly controls LDL receptor synthesis at a chromosome level and is useful for treating hyperlipidemia. SOLUTION: General formula (I) Wherein a, b and c are each independently a formula: C- Represents a group represented by H or a nitrogen atom. R 1 is substituted by the number of m, and each is independently a hydroxy group, a halogen atom, etc., m is 0 to 3, D is 1,3-phenylenediyl or the like, and Y may be substituted. Z represents a benzene ring or an optionally substituted hetero ring, The R 2 S (O) n R 3 or -S (O) n NR 4 groups represented by R 5, n is 1 or 2, R 2 and R 4 may be hydrogen atoms or substituted alkyl R 3 represents an optionally substituted alkyl group, an optionally substituted phenyl group or the like; and R 5 represents a hydrogen atom, an optionally substituted alkyl group, or an optionally substituted acyl group. Represents Or a pharmaceutically acceptable salt thereof. |