| abstract |
(57) [PROBLEMS] To suppress the expression of inflammatory proteins and the activation of gene transcription regulatory factors related thereto, and to prevent, ameliorate and / or treat diseases related to activation of inflammatory factors or skin damage and diseases. Useful inflammatory factor activation inhibitor, method for suppressing inflammatory factor activation using such an inflammatory factor activation inhibitor, and drug for specific use of inflammatory factor activation inhibitor (external skin preparation, eye drops) , Nutrients, infusion preparations, etc.), cosmetics, foods and drinks, and the like. An excellent inflammation which solves the above-mentioned problems by using a specific polysulfide derivative containing a disulfide derivative (which may be in any form such as a free form, a salt, a solvate, an ester form) as an active ingredient. A factor activation inhibitor is provided. The method is suitable for the method for suppressing the activation of the inflammatory factor, and for use as a drug for specific uses, cosmetics, food and drink, and the like. The specific polysulfide derivative used as the active ingredient also includes a novel disulfide derivative, and provides a novel derivative and a method for producing the same. |