| abstract |
PROBLEM TO BE SOLVED: To provide a common prodrug and a pharmaceutically acceptable salt of amlodipine and atorvastatin. SOLUTION: 3-Ethyl-5-methyl-2-{[2- ({7- [3-anilinocarbonyl) -5- (4-fluorophenyl) -2-isopropyl-4-phenyl-1 H-pyrrol-1-yl] -3,5-dihydroxyheptanoyl {amino) ethoxy] methyl} -4- (3-chlorophenyl) -6-methyl-1,4-dihydro-3, Common prodrugs and pharmaceutically acceptable salts of amlodipine and atorvastatin with 5-pyridinecarboxylate for the treatment of atherosclerosis, angina, hypertension and hyperlipidemia complications, and heart It is characterized in that it is used in the manufacture of a medicament for disease risk management. |