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filingDate 2001-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2002-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2002176991-A
titleOfInvention DNA chip using codon scanning algorithm
abstract (57) [Summary] (With correction) [Method] A method for preparing an oligonucleotide designed to detect a mutation present in the entire search codon region determined by a codon scanning algorithm, and a method for preparing an oligonucleotide prepared by the method. Method for producing a DNA chip using a probe, DNA chip produced by the method, and the DNA The present invention relates to a mutation detection method using a chip. [Effect] By using the DNA chip, it is possible to avoid an error caused in the analysis of the result due to a base pair mismatch found in a DNA probe designed by a conventional algorithm, and to homozygous mutation in a heterozygote. It can be distinguished from zygotic mutations, and mutations causing various genetic diseases can be detected and identified by a rapid and accurate technique. DNA chips using the codon scanning algorithm can be used for diagnosis of all gene mutations and for SNP (= Single Nucleotide). Polymorphism (-nucleotide polymorphism).
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